_1568962638 1568962638 Editor editor.jddt@gmail.com UJPR Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 04 11 2018 Shah Murad Azmat Ali Hina Aslam Khalid Niaz Cardiovascular diseases are leading cause of death in western and eastern countries of the world. Hyperlipidemia is one of the strong risk fractions for heart diseases. To evaluate hypolipidemic drugs efficacy, the study was conducted at National hospital, Lahore Pakistan from January 2016 to August 2016. Ninty hyperlipidemic patients were selected from cardiology and medical wards of the hospital. They were divided in three groups, one at placebo therapy, another on Kalonji and third one on Vitamin B3. After one and half month, significant changes (p value ranging from <0.05 to <0.001) were observed in their LDL and HDL-cholesterol. Conclusion of the study was to recommend use of herbal medicine and vitamin B3 for prevention of any heart diseases with good patient compliance. 11 01 2017 10.22270/ujpr.v2i6.R4 http://ujpr.org/index.php/journal/article/view/100 http://ujpr.org/index.php/journal/article/download/100/77 http://ujpr.org/index.php/journal/article/download/100/259 http://ujpr.org/index.php/journal/article/download/100/77 http://ujpr.org/index.php/journal/article/download/100/259