_1736921208 20250115060648000 Editor editor.jddt@gmail.com Universal Journal of Pharmaceutical Research Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 2831-5235 01 15 2025 Essam Yahiya Al-shamahi Sameha A. Al-Eryani Emad Hassan Al-Shamahi Nawal Mohammed Al-Hababi Nashwan Yahya A Al-Shamahi Hassan Abdulwahab Al-Shamahy A rare inflammatory eye illness that involves the posterior regions of the sclera. Posterior scleritis is very rare in children and more common in women. Ocular pain, headaches, and vision loss are some of its frequently vague clinical manifestations. Rheumatic conditions including systemic lupus erythematous (SLE), anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis and rheumatoid arthritis (RA) are frequently linked to the scleritis pathogenesis. A comprehensive clinical eye exam is necessary to diagnose posterior scleritis because it can mimic many other ocular disorders. Laboratory tests may reveal underlying systemic disorders, such as rheumatic disease and inflammatory markers. A precise diagnosis is aided by imaging, such as magnetic resonance imaging (MRI) and B-scan ultrasonography. Treatment includes non-steroidal anti-inflammatory drugs (NSAIDs), topical corticosteroids for moderate disease, and systemic corticosteroids for severe disease. For refractory instances, biologic therapy has grown in importance. To treat this potentially blinding condition, a multidisciplinary strategy combining rheumatology and ophthalmology is essential. This case report focuses on a 9-year-old boy who has posterior scleritis and no history of rheumatic disorders or other infections or non-infectious diseases.                   Peer Review History: Received 6 September 2024;   Reviewed 8 November; Accepted 21 December; Available online 15 January 2025 Academic Editor: Dr. Nuray Arı, Ankara University, Turkiye, ari@ankara.edu.tr Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 01 15 2025 http://creativecommons.org/licenses/by-nc/4.0 10.22270/ujpr.v9i6.1244 https://ujpronline.com/index.php/journal/article/view/1244 https://ujpronline.com/index.php/journal/article/download/1244/1769 https://ujpronline.com/index.php/journal/article/download/1244/1769 https://ujpronline.com/index.php/journal/article/download/1244/1782 https://ujpronline.com/index.php/journal/article/download/1244/1798