_1742026115 20250315080835000 Editor editor.jddt@gmail.com Universal Journal of Pharmaceutical Research Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 2831-5235 03 15 2025 Ezegbe Chekwube Andrew Ezegbe Amarachi Grace Anikwe Chidera Celestine Odo Kenechi Benjamin Onyia Oluebube Chisom Agu-kalu Amarachi Ugorji Anita Chidera Uchenna Chiamaka Precious Aerogel-based biomaterial is an important subject in materials sciences due to their vast attention in different sectors. These materials possess unique properties that distinguish them such as low density. In the area of tissue engineering, there application has been documented in areas such as blood vessel, soft tissue, nerves, bone and cartilage.There are several steps involved in aerogel preparation. The first step involves the appropriate selection of a precursor material such as polymers, silica or carbon. Aerogels have a unique property which includes the composition of mesoporous solid colloids that possess a light weight and a porous frame work structure. Aerogels also possess unique extraordinary physicochemical properties.Tissue engineering is a broad term that encompasses on using biocompatible materials to repair and replace damaged tissues. Notwithstanding, its diverse applications over the years, tissue engineering have had persistent hurdles which include the need to develop new novel biomaterials This article seeks to review the properties of aerogel and their preparation processes. The review also documented the challenges from current studies and future prospects were also discussed.              Peer Review History: Received 2 December 2024;   Reviewed 11 January 2025; Accepted 14 February; Available online 15 March 2025 Academic Editor: Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622,  Giza, Egypt, gehankandeel9@yahoo.com  03 15 2025 http://creativecommons.org/licenses/by-nc/4.0 10.22270/ujpr.v10i1.1276 https://ujpronline.com/index.php/journal/article/view/1276 https://ujpronline.com/index.php/journal/article/download/1276/1812 https://ujpronline.com/index.php/journal/article/download/1276/1812 https://ujpronline.com/index.php/journal/article/download/1276/1825 https://ujpronline.com/index.php/journal/article/download/1276/1836