_1568870386 1568870386 Editor editor.jddt@gmail.com UJPR Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 05 15 2018 Abbas Yazdanpanah Laleh Basri Boushehri Shaghayegh Vahdat Nosocomial infections are one of the social and economic medical problems in developing countries, which contribute to the spread of infectious diseases and long hospitalization and mortality among patients. The aim of this study was evaluating the knowledge, attitude and practice of hospital managers in Bushehr Province in the field of nosocomial infections. The study was a descriptive – analytic carried out on 52 managers of hospitals governmental and non – governmental in Bushehr Province in 2018. The world health organization questionnaires were used to collect knowledge, attitude and practice data. Data was analyzed by SPSS software version 20. This is a descriptive-analytic study conducted on 52 managers of governmental and semi-private hospitals in Bushehr province in 2018. The needed data on knowledge, attitude and performance was collected by 3 questionnaires published by the World Health Organization. The collected data was analyzed by SPSS statistical software version 20. The results of this study showed that 11.54% of managers had good knowledge of nosocomial  infection, 67.31% had good attitude and 42.31% of managers had advanced level of performance. There was not any significant association between knowledge and Practice and also knowledge and attitude; but there was a significant association between, attitude and practice .(p<0.05). According to the results of this study, although managers’ attitude towards nosocomial infections is quite good, most of them had not desirable knowledge and practice to prevent them. Considering the important role of managers in prevention of nosocomial infections,  it is very important to pay more attention to the training of this group in order to improve the management of infection control in hospitals. Google Scholar 05 11 2018 1 5 http://creativecommons.org/licenses/by-nc/4.0 10.22270/ujpr.v3i2.128 http://ujpr.org/index.php/journal/article/view/128 http://ujpr.org/index.php/journal/article/download/128/309 http://ujpr.org/index.php/journal/article/download/128/309