_1752555982 20250715050622000 Editor editor.jddt@gmail.com Universal Journal of Pharmaceutical Research Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 2831-5235 07 15 2025 INTERGENERATIONAL EPIGENETIC INHERITANCE: A MINIREVIEW OF MECHANISMS AND IMPLICATIONS FOR HUMAN HEALTH AND DISEASE Mostafa Essam Eissa The concept of inherited memories, where experiences from one generation can influence the traits and behaviors of subsequent generations, has long captivated scientific curiosity. Recent advancements in epigenetics have provided compelling evidence for the potential mechanisms underlying this phenomenon. This focused brief review article outlines the current state of knowledge on inherited memories, examining the transgenerational effects observed in animal models, the epigenetic mechanisms involved, and the environmental influences that shape these heritable traits. Additionally, Highlights about emerging areas of inquiry were explored, including the cross-generational transmission of social behaviors, the evolutionary implications of inherited memories, and the ethical considerations surrounding research in humans. Thus, a unique perspective could be deduced from this rapidly evolving field and accordingly, further research could be stimulated into the implication of inherited memories.                     Peer Review History: Received 6 April 2025;   Reviewed 12 May 2025; Accepted 27 June; Available online 15 July 2025 Academic Editor: Dr. Iman Muhammad Higazy, National Research Center, Egypt, imane.higazy@hotmail.com Reviewers: Dr. Eyassu Mathewos, School of public health, college of health sciences and medicine, Wolaita Soddo university- P.O. Box 158, Wolaita Soddo, Ethiopia.    Dr. Fatehalrahman F. Magbool, University of Khartoum, Sudan, fmagbool@yahoo.com 07 15 2025 http://creativecommons.org/licenses/by-nc/4.0 10.22270/ujpr.v10i3.1354 https://ujpronline.com/index.php/journal/article/view/1354 https://ujpronline.com/index.php/journal/article/download/1354/1898 https://ujpronline.com/index.php/journal/article/download/1354/1898 https://ujpronline.com/index.php/journal/article/download/1354/1908 https://ujpronline.com/index.php/journal/article/download/1354/1930