_1773586276 20260315145116000 Editor editor.jddt@gmail.com Universal Journal of Pharmaceutical Research Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 2831-5235 03 15 2026 Lutf Mohammed Al-Rahbi Ayman Ahmah Amer Hassan Abdulwahab Al-Shamahy Ahmed Abdulah Al-Ashwal Background and aims: Mandibular fractures are the most common facial trauma injuries, followed by zygomaticomaxillary complex (ZMC) fractures. The aetiology of these fractures varies greatly between nations and even regions, despite the fact that their occurrence is uniform across geographic boundaries. This study compares the results of two-point versus three-point surgical treatments for ZMC fractures. Patients and methods: Patients with zygomatico-maxillary complex fractures who received surgical treatment at the Military Hospital in Sana'a, Yemen, in 2025 were the subject of a retrospective analysis. Regarding the two-point and three-point procedures, the patients were split into two groups. Demographic information, aetiology, fracture types location, any facial injuries, kind and timing of repair, were all gathered. Results: The study involved 24 male patients with zygomatico-maxillary complex fractures, averaging 26.3 years in age, primarily due to road traffic accidents (70.8%). High Intraorbital Rim (IOR) involvement was observed in 95.8% of cases, with complications such as ocular muscle entrapment (33.3%) and inferior orbital nerve (ION) involvement (75%). Periorbital edema (79.2%) and ION paraesthesia (75%) were the most common complications. The three-point fixation technique showed a higher incidence of periorbital edema (100%) and numbness in the inferior oblique nerve (100% versus 50% for the two-point technique), alongside more lower eyelid deformities (83.3% vs 25%), Conclusions: Road traffic accidents is most common aetiology of zygomatico-maxillary complex fractures,  High intraorbital rim (IOR),  ocular muscle entrapment , inferior orbital nerve (ION) involvement, Periorbital edema and ION paresthesia were the most common complications.                   Peer Review History: Received 4 December 2025;   Reviewed 17 January 2026; Accepted  19 February; Available online 15 March 2026 Academic Editor: Prof. Dr. Gorkem Dulger, Duzce University, Turkey, gorkemdulger@yandex.com Reviewers: Dr. Kingsley C Anukam, University of Benin, Nigeria, kanukam@gmail.com Dr. Leyla Açık, Gazi University, Ankara, Turkey,  leylaacik@gmail.com 03 15 2026 http://creativecommons.org/licenses/by-nc/4.0 10.22270/ujpr.v11i1.1486 https://ujpronline.com/index.php/journal/article/view/1486 https://ujpronline.com/index.php/journal/article/download/1486/2082 https://ujpronline.com/index.php/journal/article/download/1486/2082 https://ujpronline.com/index.php/journal/article/download/1486/2083 https://ujpronline.com/index.php/journal/article/download/1486/2106