_1789449493 20260915131813000 Editor editor.jddt@gmail.com Universal Journal of Pharmaceutical Research Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 2831-5235 09 15 2026 Christian Mugabo Milk powder is a critical global commodity for nutrition and food security. Due to complex international supply chains, it remains a primary target for intentional economic adulteration, highlighting a need for rapid, nondestructive quality control beyond traditional, destructive reference methods. This manuscript provides a global review of contemporary quality control, synthesizing analytical methodologies from the IDF, ISO, and Codex Alimentarius. We systematically categorize traditional analytical techniques alongside state of the art nondestructive methods, emphasizing the integration of Fourier Transform Infrared (FTIR), Near Infrared (NIR), and Raman spectroscopy with advanced chemometrics. Our synthesis reveals a paradigm shift toward real time, field deployable diagnostics essential for mitigating food fraud across the farm to table continuum. Furthermore, the paper addresses international regulatory disparities, advocating for a hybrid validation approach that reconciles classical standards with emerging digital screening systems.                   Peer Review History: Received 2 June 2026;   Reviewed 6 July 2026; Accepted  9 August; Available online 15 September 2026 Academic Editor: Dr. Asia Selman Abdullah, Pharmacy institute, University of Basrah, Iraq, asia_abdullah65@yahoo.com Reviewers: Dr. Amany Mohamed Alboghdadly, Ibn Sina National College for Medical Studies in Jeddah, Saudi Arabia, amanyalboghdadly@gmail.com  Prof. Ali Gamal Ahmed Al-kaf, Sana'a university, Yemen, alialkaf21@gmail.com 09 15 2026 http://creativecommons.org/licenses/by-nc/4.0 10.22270/ujpr.v11i4.1635 https://ujpronline.com/index.php/journal/article/view/1635 https://ujpronline.com/index.php/journal/article/download/1635/2234 https://ujpronline.com/index.php/journal/article/download/1635/2234 https://ujpronline.com/index.php/journal/article/download/1635/2248 https://ujpronline.com/index.php/journal/article/download/1635/2262