_1568708391 1568708391 Editor editor.jddt@gmail.com UJPR Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 05 15 2019 Samir Ahmed Ali ALhaidari Qais Abdullah Aziza M. Taj Al-Deen Fatima A. Al-Hadi Anas AL Mahbashi Ali Gamal Al-Kaf Fouad A. Al-Dubai In this study methanolic and aqueous extracts of one plant namely Psidium guajava, were screened for the presence of phytochemical constituents and tested for their antimicrobial and antioxidant activity. The qualitative phytochemical analysis revealed the results showed presence of alkaloids, terpenoids, glycosides, resins, saponins, tannins, flavonoids, phenols, and amino acid were present in the methanol extract, with absence of glycosides, and amino acids in the aqueous extracts in leaves plant. TLC tests conducted revealed Rf values in the leaves for alkaloids, Flavonoids, Tannins, Phenols and Saponins(0.96-0.97-0.99-0.97-0.99) respectively. The antimicrobial activity extracts against four bacterial isolates Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella sp. and a single fungal isolate Candida albicans with concentrations (0.5 mg/ml, and 1,0 mg/ml) of the extract were added to the disc and respective solvent was used as negative control. The antioxidative activity of leaf was evaluated by using 1,1- diphenyl-2 picrylhydrazyl (DPPH), the results showed are 88.4%, highest from standard, ascorbic acid 87.5%. 05 05 2019 10.22270/ujpr.v4i2.250 http://ujpr.org/index.php/journal/article/view/250 http://ujpr.org/index.php/journal/article/download/250/170 http://ujpr.org/index.php/journal/article/download/250/284 http://ujpr.org/index.php/journal/article/download/250/170 http://ujpr.org/index.php/journal/article/download/250/284