_1568956112 1568956112 Editor editor.jddt@gmail.com UJPR Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 04 11 2018 Usman Mohammed Jajere Achadu A E The objective of the present study was to formulate solid dispersions (SD) of Ezetimibe to improve the solubility and dissolution rate to facilitate faster onset of action. Ezetimibe is a poorly water soluble BCS class II drug and used as a hypolipidemic agent. It has poor bioavailability (35-65%) due to its low dissolution profile in gastro intestinal tract. In the present study, eight solid dispersion formulations of Ezetimibe with polymers PEG-4000 and PEG-6000 were prepared by solvent evaporation and fusion methods.  Solid dispersion formulations were characterized by content uniformity, flow properties and in vitro dissolution studies. Present study concluded that the Ezetimibe solid dispersion formulations are a suitable approach to improve the solubility and dissolution rate of ezetimibe than pure form of drug. Google Scholar 01 01 2017 10.22270/ujpr.v2i1.R3 http://ujpr.org/index.php/journal/article/view/33 http://ujpr.org/index.php/journal/article/download/33/24 http://ujpr.org/index.php/journal/article/download/33/211 http://ujpr.org/index.php/journal/article/download/33/24 http://ujpr.org/index.php/journal/article/download/33/211