<?xml version="1.0" encoding="utf-8"?>
<doi_batch xmlns="http://www.crossref.org/schema/4.3.6" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:jats="http://www.ncbi.nlm.nih.gov/JATS1" xmlns:ai="http://www.crossref.org/AccessIndicators.xsd" version="4.3.6" xsi:schemaLocation="http://www.crossref.org/schema/4.3.6 https://www.crossref.org/schemas/crossref4.3.6.xsd">
  <head>
    <doi_batch_id>_1568956980</doi_batch_id>
    <timestamp>1568956980</timestamp>
    <depositor>
      <depositor_name>Editor</depositor_name>
      <email_address>editor.jddt@gmail.com</email_address>
    </depositor>
    <registrant>UJPR</registrant>
  </head>
  <body>
    <journal>
      <journal_metadata>
        <full_title>Universal Journal of Pharmaceutical Research</full_title>
        <abbrev_title>Univ J Pharm Res</abbrev_title>
        <issn media_type="electronic">2456-8058</issn>
      </journal_metadata>
      <journal_issue>
        <publication_date media_type="online">
          <month>04</month>
          <day>11</day>
          <year>2018</year>
        </publication_date>
      </journal_issue>
      <journal_article xmlns:jats="http://www.ncbi.nlm.nih.gov/JATS1" publication_type="full_text" metadata_distribution_opts="any">
        <titles>
          <title>DEVELOPMENT AND EVALUATION OF TRANSDERMAL GEL OF LORNOXICAM</title>
        </titles>
        <contributors>
          <person_name contributor_role="author" sequence="first">
            <given_name>Saifullahi</given_name>
            <surname>Umar</surname>
          </person_name>
          <person_name contributor_role="author" sequence="first">
            <given_name>Moh Kingsley</given_name>
            <surname>Onyekachi</surname>
          </person_name>
        </contributors>
        <jats:abstract xmlns:jats="http://www.ncbi.nlm.nih.gov/JATS1">
          <jats:p>The objective of the present study was to formulate solid dispersions (SD) of Ezetimibe to Transdermal drug delivery systems deliver the drug through the skin at controlled rate to the systemic circulation. It maintains the blood concentration of the drug within the therapeutic system window ensuring that drug levels neither fall below the minimum effective concentration nor exceed the minimum toxic dose. The objective of the present work was to formulate transdermal gel of Lornoxicam. It is a COX-1 and COX-2 inhibitor used in the treatment of inflammation, pain and edema, rheumatoid arthritis. Transdermal gel of Lornoxicam was formulated using triethanolamine as solvent, HPMC K100 and EC as polymers. Formulated gel was evaluated with respect to different physiochemical parameters such as pH, viscosity, spreadability.  In–vitro release study was performed for 10 hrs.  Selected formulation was subjected to stability testing at different temperatures.&#13;
Google Scholar</jats:p>
        </jats:abstract>
        <publication_date media_type="online">
          <month>01</month>
          <day>01</day>
          <year>2016</year>
        </publication_date>
        <doi_data>
          <doi>10.22270/ujpr.v2i1.R4</doi>
          <resource>http://ujpr.org/index.php/journal/article/view/34</resource>
          <collection property="crawler-based">
            <item crawler="iParadigms">
              <resource>http://ujpr.org/index.php/journal/article/download/34/25</resource>
            </item>
          </collection>
          <collection property="crawler-based">
            <item crawler="iParadigms">
              <resource>http://ujpr.org/index.php/journal/article/download/34/212</resource>
            </item>
          </collection>
          <collection property="text-mining">
            <item>
              <resource mime_type="application/pdf">http://ujpr.org/index.php/journal/article/download/34/25</resource>
            </item>
            <item>
              <resource mime_type="text/html">http://ujpr.org/index.php/journal/article/download/34/212</resource>
            </item>
          </collection>
        </doi_data>
      </journal_article>
    </journal>
  </body>
</doi_batch>
