_1584254648 1584254648 Editor editor.jddt@gmail.com UJPR Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 03 15 2020 Lysher Tan Shu Phing https://orcid.org/0000-0002-6504-4608 Muhammad Shahzad Aslam https://orcid.org/0000-0002-6504-4608 Tramadol, which is a medication used for moderate and severe pains, has caused drug abuse and addiction to the Egyptian community. This study aimed to observe the prevalence of tramadol abuse among Egyptian university students. By following the PRISMA reporting guideline, a systematic review of evidence was conducted. Search strategy was conducted through PubMed-NCBI to yield appropriate published literature between 2014-2019, as well as performed literature screening, eligibility criteria, and data extraction. The process of selection yielded a total number of 2 studies to be eligible for the review inclusion criteria. The characteristics evaluated that correlate to tramadol were classified into four groups: gender, smoking, alcohol consumption, and failure in exams before. In general, tramadol showed positively associated with other prevalence characteristics. Tramadol is the second most commonly abused drug among university students in Egypt. The review highlights that tramadol abuse has become a common phenomenon among Egyptian university students which necessitates for ample attention. Future research is recommended to identify the causal effects of tramadol abuse and its role as a potential gateway drug. Peer Review History: Received 2 January 2020;   Revised 22 February; Accepted 1 March, Available online 15 March 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Hebatallaha A  Moustafa Affiliation: Ain Shams University, Egypt E-mail: anasweety2003@yahoo.com   Name: Dr. Hassan A.H. Al-Shamahy Affiliation: Sana'a University, Yemen E-mail: shmahe@yemen.net.ye   Name: Dr. Ali Abdullah Al-yahawi Affiliation: Al-Razi university, Department of Pharmacy, Yemen E-mail: alyahawipharm@yahoo.com Comments of reviewer(s): Similar Articles: A CROSS-SECTIONAL STUDY ON BENZODIAZIPINE (BZD) ABUSERS OF DHAKA CITY: A SOCIO-PSYCHOLOGICAL CONDITION OF BANGLADESH AWARENESS AMONGST YOUTH ABOUT USE AND ABUSE OF STEROIDS IN KARACHI, PAKISTAN ALCOHOL INFLUENCES AGGRESSIVE BEHAVIOUR THAT INCREASES LIKELIHOOD OF INITIATING DATING VIOLENCE AMONG MALE YOUTH IN COLLEGES WITHIN WESTERN COUNTRIES: A SCOPING REVIEW 03 08 2020 10.22270/ujpr.v5i1.363 http://ujpr.org/index.php/journal/article/view/363 http://ujpr.org/index.php/journal/article/download/363/643 http://ujpr.org/index.php/journal/article/download/363/656 http://ujpr.org/index.php/journal/article/download/363/666 http://ujpr.org/index.php/journal/article/download/363/643 http://ujpr.org/index.php/journal/article/download/363/656 http://ujpr.org/index.php/journal/article/download/363/666