_1589539353 1589539353 Editor editor.jddt@gmail.com UJPR Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 05 15 2020 Jamal A. N. Al-Mahweety https://orcid.org/0000-0002-8425-925X Sadeq HS Azzam https://orcid.org/0000-0002-0367-388X Ali Alyahawi https://orcid.org/0000-0002-1099-7778 Objectives:  Caralluma belongs to the family Asclepiadaceae, native to the Indian sub-continent have different medicinal properties and used in folk medicine as remedies to treat wide variety of diseases and health conditions. Objective of present study was to isolate, analyze and identify the phytochemicals composition from steam of Caralluma  quadrangula. Methods:  Extractions of the chemical components was carried out by different chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry. Results:  The quantitative phytochemical analysis of this species exhibited the presence of three compounds, Glochidonol (5gm), Dihydroxy-14-pregn-5-en-20-one (9.8gm), Hydroxystigmast-5-en-7-one (7.8gm) and Stigmasterol (5.7 mg). Hydroxystigmast-5-en-7-one, report from Caralluma  quadrangula stem as first time.     Conclusion:  The present study is strengthen for the discovery three pure chemical compounds from C. quadrangula. Peer Review History: Received 2 April 2019; Revised 22 April; Accepted 7 May, Available online 15 May 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 4.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Ahmad Najib Affiliation: Universitas Muslim Indonesia, Makassar, Indonesia E-mail: ahmad.najib@umi.ac.id   Name: Dr. Hatem Sameir Abbas Affiliation: Al-Azhar University, Egypt E-mail: hsam8406@yahoo.com Comments of reviewer(s): Similar Articles: A REVIEW ON CONSTITUENTS, PHARMACOLOGICAL ACTIVITIES AND MEDICINAL USES OF GLYCYRRHIZA GLABRA MURRAYA KOENIGI-A BOON IN DIFFERENT PATHOLOGICAL CONDITIONS 05 15 2020 10.22270/ujpr.v5i2.385 https://www.ujpr.org/index.php/journal/article/view/385 https://www.ujpr.org/index.php/journal/article/download/385/678 https://www.ujpr.org/index.php/journal/article/download/385/692 https://www.ujpr.org/index.php/journal/article/download/385/705 https://www.ujpr.org/index.php/journal/article/download/385/678 https://www.ujpr.org/index.php/journal/article/download/385/692 https://www.ujpr.org/index.php/journal/article/download/385/705