_1678857032 20230315051032000 Editor editor.jddt@gmail.com Universal Journal of Pharmaceutical Research Universal Journal of Pharmaceutical Research Univ J Pharm Res 2456-8058 03 15 2023 Gamil Amin Abdulla Ali Al-Ghaithi https://orcid.org/0000-0002-4586-8167 Khaled Abdulkareem Al-Moyed https://orcid.org/0000-0002-0538-6227 Hassan Abdulwahab Al-Shamahy https://orcid.org/0000-0001-6958-7012 Ahmed Mohamed Al-Haddad https://orcid.org/0000-0002-9844-7868 Background and objectives: Food borne diseases are a global public health problem and food handlers play a major role for the transmission of food borne diseases. This study was aimed at exploring the prevalence of intestinal parasites, Salmonella typhi carrier rate and risk factors of infection with typhoid and/or intestinal parasites among food handlers at Ibb city, Yemen. Subjects and methods: A cross sectional survey was conducted among three hundred and fifteen food handlers, in age ranges from 14 to 65 years. All individuals were working in restaurants, cafeterias or school buffets in Ibb city. For collecting data; a pre-tested structured questionnaire was used. Stool samples were examined for intestinal parasites microscopy and for S. typhi by stool culture media and blood for detection antibodies per the standard laboratory methods were used. Results: A total of 315 food handlers in Ibb city over a 12-month period were enrolled in this study, ages ranged from 14 to 65 years, with a mean±SD age of 31.2±11.9 years. The highest prevalence of antibodies against S. typhi antigen suspension O was 18.4%, while antibodies against S. typhi H antigen suspension were 7.6%. Also, the positive rate for total S. typhi antibodies ELISA IgG was 9.5% and the positive rate for S. typhi stool cultures was 7.3%.  The overall prevalence of intestinal protozoa was 20%, the most intestinal parasitic prevalent was Entamoeba histolytica (15.6%), followed by Ascaris lumbricoides (12.1%), Hymenolepis nana (4.4%), and Schistosoma mansoni (3.2%). Conclusion: Inexperienced and poor personal hygienic food handlers play a role in the transmission of food-borne infections. Local health authorities should implement food handlers training on food safety, institute periodic focused medical check-up for food handlers and improve human waste disposal.                          Peer Review History: Received: 4 January 2023; Revised: 13 February; Accepted: 8 March 2023, Available online: 15 March 2023 Academic Editor: Dr. A.A. Mgbahurike, University of Port Harcourt, Nigeria, amaka_mgbahurike@yahoo.com Received file:                             Reviewer's Comments: Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewers: Rola Jadallah, Arab American University, Palestine, rola@aauj.edu Dr. Tamer Elhabibi, Suez Canal University, Egypt, tamer_hassan@pharm.suez.edu.eg Dr. Wadhah Hassan Ali Edrees, Hajja University, Yemen, edress2020@gmail.com Dr. Rawaa Souhil Al-Kayali, Aleppo University, Syria, rawah67@hotmail.com Similar Articles: EVALUATION OF ANTIBACTERIAL RESISTANCE OF BIOFILM FORMS OF AVIAN SALMONELLA GALLINARUM TO FLUOROQUINOLONES 03 15 2023 http://creativecommons.org/licenses/by-nc/4.0 10.22270/ujpr.v8i1.890 https://ujpr.org/index.php/journal/article/view/890 https://ujpr.org/index.php/journal/article/download/890/1342 https://ujpr.org/index.php/journal/article/download/890/1342 https://ujpr.org/index.php/journal/article/download/890/1352 https://ujpr.org/index.php/journal/article/download/890/1364