THE ASSOCIATION BETWEEN HEPATITIS B VIRUS INFECTION WITH ABO AND RHD BLOOD GROUPS

Sadeq Kaid Mohammed Al-Mohani; Ebraheem Ali Ahmed Al-Nawd

doi:10.22270/ujpr.v9i3.1115

Sadeq Kaid Mohammed Al-Mohani Dean of Faculty of Medical Laboratories, Jiblah University for Medical and Health Sciences, Ibb Governorate, Yemen.
Ebraheem Ali Ahmed Al-Nawd Division of Clinical Biochemistry, Department of Chemistry, Faculty of Medical Laboratories Sciences, Jiblah University for Medical and Health Sciences, Ibb Governorate, Yemen.

10.22270/ujpr.v9i3.1115

Keywords:

Blood group, Hepatitis B infection, Jiblah, RhD, Yemen

Abstract

Background: ABO and Rh blood types are associated with a higher risk of disease and are essential for clinical practice and blood transfusion safety. The findings of earlier research on the relationship between blood types and HBV infection are still up for debate. There is no study conducted on the study population to reveal the relationship between ABO and RhD blood groups and infection with hepatitis B virus.

Aims: This study aimed to identify the relationship between blood types and hepatitis B virus infection in blood donors at Jiblah University Hospital in Jiblah town, Yemen

Methods: A hospital-based cross-sectional study was conducted. Venous blood samples were drawn from 120 blood donors and tested for hepatitis B core antigen (anti-HBc) using commercial kits (Roche Diagnostics GmbH, United Kingdom). ABO and Rh blood groups were determined by the cell pooling method. The results were analyzed using SPSS v.20.

Results: This study reported that the most frequent blood types were O positive and A positive 57 (47.5%) and 28 (23.3%) respectively, followed by B positive 14 (11.67%) and O negative 13 (10.83%). The overall phenotypic frequencies of ABO and RhD blood groups were O+>A+>B+>O->A->AB+>B->AB-. The prevalence of hepatitis B virus was 12 (10%). No statistical association was detected between ABO and RhD blood groups and hepatitis B infection.

Conclusions: High prevalence rates of hepatitis B virus infection among blood donors were identified in this study. There was no statistical association between ABO and RhD blood groups and hepatitis B infection.