PHYTOCHEMICAL PURIFICATION OF ACTIVE CONSTITUENTS ISOLATED FROM ROOT OF THE MEDICINAL HERB, CARALLUMA QUADRANGULA

Abstract

Objective: Present study aim for the purification of quantitative phytochemical compounds from roots of  Caralluma quadrangula belongs to the family Asclepiadaceae. This type of plants can be use as folk medicine  to take care of wide diversity of health  and diseases situation.

Methods: Preliminary phytochemical analysis for different type of chemical compounds by using various  chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry.

Results: The quantitative phytochemical analysis of this species exhibited the presence four pure compounds,  hydroxyoplopan-4-one (4.5 mg), dihydroxyeudesm-4(15)-ene (5.0 mg), and quercetin- rhamnopyranosyl-D-glucopyranose (Rutin) (7.0 mg).

Conclusion: From this study, it can be concluded that the species found four pure compounds from C. quadrangula.

                   

Peer Review History:

Received 6 June 2020; Revised 11 July; Accepted 25 August; Available online 15 September 2020

Academic Editor: Dr. Nuray Arı, Ankara University, Turkiye, ari@ankara.edu.tr

 Received file:                Reviewer's Comments:

Average Peer review marks at initial stage: 5.0/10

Average Peer review marks at publication stage: 7.5/10

Reviewer(s) detail:

Dr. Marwa  A. A. Fayed, Faculty of Pharmacy, University of Sadat City, Egypt, maafayed@gmail.com

Prof.  Dr. Ali Gamal Ahmed Al-kaf, Sana'a university, Yemen, alialkaf21@gmail.com

Ahmad Najib, Department of Pharmacognosy-Phytochemystry Universitas Muslim Indonesia-Indonesia, ahmad.najib@umi.ac.id