INVESTIGATION OF LIPOIDIAL CONTENTS AND THEIR ANTIMICROBIAL ACTIVITY OF FORSSKAOLEA VIRIDIS AND TRICHODESMA EHRENBERGII WILDLY DISTRIBUTED IN EGYPT

Abstract

Objective: The aim of this work was to assess the antimicrobial activity and investigation of lipoidial contents of F. viridis and T. ehrenbergii wildly distributed in Gebel Elba, Southeast of Egypt for the first time.

Methods: The phytochemical investigation of the ether extracts of  F. viridis and T. ehrenbergii carried out by saponification of two lipoidial extracts and  using gas chromatography (GC) with reference standards. The antimicrobial activity of the ether extract was performed as in vitro studies by diffusion agar technique for selected +ve and –ve gram bacterial and fungal strains with reference used drug as a control.

Results: The findings of this study revealed that the two lipoidial extracts have sufficient steroidal and fatty acid methyl ester compounds  where F. viridis contain (22) hydrocarbons, (6) sterols and (14) fatty acid methyl esters while, T. ehrenbergii contain (20) hydrocarbons, (5) sterols and (17) fatty acids where β-amyrin and stigmasterol and palmitic and Tricyclic acid were the major concentration of steroid and fatty acid methyl ester contents of F. viridis and T. ehrenbergii respectively. The lipoidial extract of F. viridis and T. ehrenbergii exhibited moderate antimicrobial activity against all tested strains as compared to reference used drug.

Conclusion: It can be elicited that the ethereal extracts of two plants have moderate antimicrobial activity against selected strains.

                              

Peer Review History:

Received 3 October  2020; Revised 10 November; Accepted 21 December; Available online 15 January 2021

Academic Editor: Prof. Kumud Upadhyaya, Kumaon University, Nainital, UK, India, upkuupku@gmail.com

Received file:                Reviewer's Comments:

Average Peer review marks at initial stage: 5.5/10

Average Peer review marks at publication stage: 7.5/10

Reviewer(s) detail:

Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id

Dr. Mohamed Said Fathy Al-Refaey, University of Sadat City, Menofia, Egypt, Mohamed.said@fop.usc.edu.eg