IN VITRO EVALUATION OF THE ANTIMICROBIAL ACTIVITY OF FIVE HERBAL EXTRACTS AGAINST STREPTOCOCCUS MUTANS

Eman Mohammed Abduljalil Gylan; Bushra Abdulkarim Muharram; Abdulwahab Ismail Mohamed Al-Kholani; Khaled A AL-Haddad; Ameen Abdullah Yahya Al-Akwa; Hassan Abdulwahab Al-Shamahy; Mohsen  Ali Al-Hamzi; Mohammed A Al-labani

doi:10.22270/ujpr.v7i1.721

Eman Mohammed Abduljalil Gylan Department of conservative dentistry, Faculty of Dentistry, Sana’a, University, Republic of Yemen.
Bushra Abdulkarim Muharram Department of Pharmacognosy, Faculty of pharmacy, Sana’a University Republic of Yemen.
Abdulwahab Ismail Mohamed Al-Kholani Department of conservative dentistry, Faculty of Dentistry, Sana’a, University, Republic of Yemen.
Khaled A AL-Haddad Orthodontics, Pedodontics and Prevention Department Faculty of Dentistry, Sana'a University, Yemen.
Ameen Abdullah Yahya Al-Akwa Orthodontics, Pedodontics and Prevention Department Faculty of Dentistry, Sana'a University, Yemen.
Hassan Abdulwahab Al-Shamahy Departement of Basic Sciences, Faculty of Dentistry, Sana’a University, Republic of Yemen. Medical Microbiology department, Faculty of Medicine, Genius University for Sciences and Technology, Dhamar city, Republic of Yemen.
Mohsen Ali Al-Hamzi Department of conservative dentistry, Faculty of Dentistry, Sana’a, University, Republic of Yemen.
Mohammed A Al-labani Orthodontics, Pedodontics and Prevention Department Faculty of Dentistry, Sana'a University, Yemen.

10.22270/ujpr.v7i1.721

Keywords:

Antibacterial activities, Boswellia carteril, Commiphora myrrha, Dracaena cinnabari, Salvia officinalis, Saussurea lappa, Streptococcus mutans

Abstract

Background: The emergence and extend of antibiotic resistance, together with the development of new strains of illness causes, are of enormous alarm to the global health community. Successful treatment of a illness involves the development of new pharmaceuticals or some promise source of novel drugs. Universally make use of medicinal plants of our community could be an outstanding source of drugs to fight off dental caries. This study is focused on discovering the antibacterial properties of the plants that are frequently being used as traditional medications.

Methods: Five methanol extracts from Salvia officinalis, Commiphora myrrha, Boswellia carteril, Saussurea lappa and Dracaena cinnabari were examined for their antibacterial activities against most common bacterial oral pathogen, Streptococcus mutans. The antibacterial testing was carried out by using the disc diffusion and broth micro-dilution assays.

Results: Methanol extracts of the five plants were effective against Streptococcus mutans with diameter zone of inhibition ranging from 63.6 to 21.0 mm. The results of the microdilution assay confirmed that the Salvia officinalis, Commiphora myrrha, Saussurea lappa and Dracaena cinnabari were effective against the Streptococcus mutans, exhibiting MIC values, ranging from 0.310 to 0.156 mg/ml.

Conclusion: The results of our study indicate that the methanol extracts of plants used in this study have an antibacterial effect even at low concentration against the carcinogenic Streptococcus mutans bacteria, and they may be possible to combat Streptococcus mutans to increase the effectiveness of oral hygiene practices by incorporating the extracts of these plants into anti-caries such as Toothpastes and mouthwash.