AMELOBLASTOMA IN POPULATION OF YEMEN: ANALYZING THE PREVALENCE AND CLINIC PATHOLOGIC FEATURES OF AMELOBLASTOMA IN A YEMENI POPULATION

Samar Sultan Al-Thobhani; Sam Abd Alkarem Da'er; Khaled A AL-Haddad; Khaled Abdulkarim Al-Moyed; Taghreed Ahmed M Al-Kibsi; Hassan Abdulwahab  Al-Shamahy

doi:10.22270/ujpr.v9i5.1195

Samar Sultan Al-Thobhani Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Sana'a University, Republic of Yemen.
Sam Abd Alkarem Da'er Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Sana'a University, Republic of Yemen.
Khaled A AL-Haddad Orthodontics, Pedodontics and Prevention Department Faculty of Dentistry, Sana'a University, Yemen.
Khaled Abdulkarim Al-Moyed Medical Microbiology and Clinical Immunology Department, Faculty of Medicine and Health Sciences, Sana’a University.
Taghreed Ahmed M Al-Kibsi Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Sana'a University, Republic of Yemen.
Hassan Abdulwahab Al-Shamahy Department of Basic Sciences, Faculty of Dentistry, Sana’a University, Republic of Yemen. Medical Microbiology and Clinical Immunology Department, Faculty of Medicine and Health Sciences, Sana’a University.

10.22270/ujpr.v9i5.1195

Keywords:

Ameloblastoma, odontogenic tumors, oral tumors prevalence, Yemen

Abstract

Background and aims: Ameloblastoma is an uncommon tumor of odontogenic epithelium (ameloblasts, or the outer part of the teeth during development) that can be benign or malignant. It usually appears in the lower jaw rather than the upper jaw. The initial ameloblastoma is often treated with radical tumor resection. Analyzing the prevalence and clinic pathologic features of ameloblastoma in a Yemeni population was the goal.

Material and Methods: This retrospective cross-sectional study was carried out in all patients who were diagnosed with oral tumors at the targeted centers in Sana’a city (Al-Mamoon Center, Central Laboratory, and Al-Awlqy Laboratory Centers) in the period June 2020 to June 2022. This study is based on data taken from patients’s files that include age, gender, location, and histopathology. The study used descriptive statistics and SPSS version 26 for data analysis, describing quantitative non-parametric data using median and parametric data using mean and standard deviation.

Results: The ameloblastoma tumor prevalence was 8.8% of all oral tumors (330 cases). The mean age of the ameloblastoma patients was 31.10±11.4 (± SD) years and ranged from 11 to 80 years, with 1:1.2 males to females. The majority of ameloblastoma cases occurred in the lower jaw (93.1%; N=27), and the posterior part of the lower jaw was the main site for ameloblastoma tumors (79.3%; N=23), and 86.2%; N=23 of ameloblastoma was epithelial origin and 13.8%; N=4 was variegated origin. In terms of histological type, 65.5%; N=19 of the cases were not diagnosed, and the remaining cases showed a rate of 24.1%; N=7 for a multicystic tumor and 10.3%; N=3 for a unicystic tumor. 96.6%; N=28 of ameloblastoma cases were benign tumors, and only 3.4%; N=1 case was a malignant tumor.

Conclusions: The prevalence of ameloblastoma was significant, and these findings increase the awareness level of determent type of lesion for better diagnosis, management, and preventing measures.

Peer Review History:

Received 20 July 2024; Reviewed 6 September 2024; Accepted 16 October; Available online 15 November 2024

Academic Editor: Dr. Amany Mohamed Alboghdadly, Ibn Sina National College for Medical Studies in Jeddah, Saudi Arabia, amanyalboghdadly@gmail.com

Average Peer review marks at initial stage: 6.5/10

Average Peer review marks at publication stage: 7.5/10

Reviewers:

Dr. Gülay B Anadolu, Anadolu University, Eskisehir, Turkey, gbuyukko@anadolu.edu.tr

Dr. Sheikh Abdul Khaliq, Department of Pharmacy Practice, Faculty of Pharmacy, Hamdard University, Karachi, Pakistan, drwadhsheikh1974@gmail.com