CORRELATION BETWEEN TISSUE DOPPLER IMAGING AND LEFT VENTRICULAR SYSTOLIC FUNCTION AMONG YEMENI PATIENTS AT MILITARY CARDIAC CENTRE
Keywords:
Heart failure, left ventricular ejection fraction, Simpson’s method, systolic myocardial velocity, tissue doppler imaging, YemenAbstract
Background and objective: High rates of morbidity and mortality are associated with heart failure, and these rates rise as the population ages. The purpose of the study was to compare left ventricular ejection fraction (LVEF) using Simpson's technique and systolic myocardial velocity (Sm) using tissue Doppler imaging (TDI) in Yemeni patients with heart failure (HF).
Method: This study was conducted at the Military Cardiac Centre in Sana'a, Yemen, offering diagnostics, therapeutics, and surgical services to the Yemeni population. It was a 1:2 unmatched case-control study conducted from April 1 to September 30, 2025, involving a total of 180 participants (60 cases with an ejection fraction < 55% and 120 controls with an ejection fraction > 55%). Participants provided verbal consent and underwent clinical examinations, including electrocardiography.
Results: The study compares ejection fraction (EF) results across different measurement methods, showing mean EF values of 42.25 (M mod), 37.41 (Simpson), and 38.33 (eyeballing), with a significant p-value (<0.001) between cases and controls. In systolic left ventricle (LV) parameters, case means for S med (6.6) and S lat (7.26), along with MAPSE M (9.41) and MAPSE I (11.44), were recorded with a significant p-value (<0.001). Correlations were noted for S med (0.62) and S lat (0.60), with odds ratios (26.17–17.70) and confidence intervals (CI=3.59–2.99).
Conclusions: This study finds a strong positive correlation between TDI-derived S′ velocity and left ventricular ejection fraction (LVEF), identifying S′ as a reliable marker of systolic function. It also supports MAPSE as an effective and clinically relevant marker, especially in low-resource settings.
Peer Review History:
Received 5 April 2026; Reviewed 8 May 2026; Accepted 10 June; Available online 15 July 2026
Academic Editor: Dr. DANIYAN Oluwatoyin Michael
, Obafemi Awolowo University, ILE-IFE, Nigeria, [email protected]
Reviewers:
Dr. George Zhu, Tehran University of Medical Sciences, Tehran, Iran, [email protected]
Dr. Gülay B Anadolu, Anadolu University, Eskisehir, Turkey, [email protected]
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