A STUDY OF PHYTOCHEMICAL CONSTITUENTS IN CARALLUMA  QUADRANGULA

Jamal A. N. Al-Mahweety; Sadeq HS Azzam; Ali Alyahawi

doi:10.22270/ujpr.v5i2.385

Jamal A. N. Al-Mahweety School of Chemical Sciences, Faculty of Science, Sana'a University, Yemen
Sadeq HS Azzam School of Chemical Sciences, Faculty of Science, Sana'a University, Yemen
Ali Alyahawi Faculty of Medical Sciences, Department of Pharmacy Al-Razi University, Yemen

10.22270/ujpr.v5i2.385

Keywords:

Caralluma quadrangula, Glochidonol, 3,14-dihydroxy-14-pregn-5-en-20-one, 3-Hydroxystigmast-5-en-7-one, Stigmasterol

Abstract

Objectives: Caralluma belongs to the family Asclepiadaceae, native to the Indian sub-continent have different medicinal properties and used in folk medicine as remedies to treat wide variety of diseases and health conditions. Objective of present study was to isolate, analyze and identify the phytochemicals composition from steam of Caralluma quadrangula.

Methods: Extractions of the chemical components was carried out by different chromatographic techniques. The phytochemical characterizations were evaluated by nuclear magnetic resonance and mass spectrometry.

Results: The quantitative phytochemical analysis of this species exhibited the presence of three compounds, Glochidonol (5gm), Dihydroxy-14-pregn-5-en-20-one (9.8gm), Hydroxystigmast-5-en-7-one (7.8gm) and Stigmasterol (5.7 mg). Hydroxystigmast-5-en-7-one, report from Caralluma quadrangula stem as first time.

Conclusion: The present study is strengthen for the discovery three pure chemical compounds from C. quadrangula.