INFLAMMATORY BOWEL DISEASE: CLINICAL FEATURES AND MANIFESTATIONS BEYOND THE BOWEL

Maged Almezgagi; Yu Zhang; Fadhl Al-shaebi; Mueataz A. Mahyoub; ALariqi Reem; Muhammad Shoaib; Emad Shamsan; Mohammed Gamah; Kamal Hezam; Abdul Baset Abbas; Wang Xiaozhou; Shen Xiangqun; Ma Qianqian; Ying Han; Ruhan Jia; Wei Zhang

doi:10.22270/ujpr.v5i3.422

Maged Almezgagi The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China. Department of Immunology, of Qinghai University, Qinghai Xining 810001, China.Department of Medical Microbiology, Faculty of Sciences, Ibb University, Ibb City 70270, Yemen.
Yu Zhang Department of Immunology, of Qinghai University, Qinghai Xining 810001, China.
Fadhl Al-shaebi Department of Immunology, Hebei Medical University, Shijiazhuang, Hebei 050017, China.
Mueataz A. Mahyoub Department of Gastroenterology, Second Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an710004
ALariqi Reem Department of Microbiology,Harbin Medical University,Harbin 150081,China.
Muhammad Shoaib The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China.
Emad Shamsan Department of Immunology, of Qinghai University, Qinghai Xining 810001, China.
Mohammed Gamah The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China. Department of Immunology, of Qinghai University, Qinghai Xining 810001, China.
Kamal Hezam Nankai University School of Medicine, Tianjin 300071, PR China.
Abdul Baset Abbas Department of Medical Microbiology, Faculty of Sciences, Ibb University, Ibb City 70270, Yemen.
Wang Xiaozhou The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China.
Shen Xiangqun The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China.
Ma Qianqian The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China.
Ying Han The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China.
Ruhan Jia The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China.
Wei Zhang The Key Laboratory of high-altitude medical application of Qinghai Province, Qinghai Xining 810001, China. Department of Immunology, of Qinghai University, Qinghai Xining 810001, China.

10.22270/ujpr.v5i3.422

Keywords:

Crohn's disease, inflammatory bowel disease, Ulcerative colitis

Abstract

Inflammatory bowel disease (IBD) encompasses a spectrum of diseases, with Crohn's disease (CD) and ulcerative colitis (UC) representing the two broadest subtypes of IBD. Multiple extraintestinal manifestations (EIMs) are more frequent in (IBD); 5% –50% of the patients might be affected. The most often implicated sites of manifestations are musculoskeletal and dermatological structures. However, while some symptoms like peripheral arthritis and erythema nodosum correlate with IBD progression, others have their own course of disease like axial arthropathy, gangrenosis of the pioderma and primary sclerosic cholangitis. This review would provide a summary of the most frequent EIMs and their prevalence.