NANOSPONGES: A NEW ERA OF VERSATILE DRUG DELIVERY SYSTEM

Abstract

Nanotechnology is a multi disciplinary science which is getting considerable attention in development of new chemical entities, diagnosis and treatment of several ailments. Nanomedicine technology has developed many drug delivering systems like nanoparticles, nanoemulsions, nanosuspensions, nanosponges etc., which are associated with many advantages including improved bioavailability. Nanosponges are tiny sponges having size of about a virus and can be filled with variety of drugs. This sponge can circulate around the body until interact with specific target site and stick on surface and start releasing drug in a controlled manner. Nanosponges play vital role in targeting drug delivery in a controlled manner. Both lipophilic and hydrophilic drugs are incorporated in nanosponges. The outer surface is typically porous, allowing controlled release of drug. Important characteristic of these sponges is their solubility in aqueous form and suitable for the drugs with poor solubility. This review is focusing on the preparation methods, applications of nanosponges in the field of drug delivery.

     

Peer Review History:

Received 5 April 2017;   Revised 11 May; Accepted 29 June, Available online 15 July 2017

Academic Editor: Dr. DANIYAN Oluwatoyin Michael, Obafemi Awolowo University, ILE-IFE, Nigeria, toyinpharm@gmail.com

Received file:        Reviewer's Comments:

Average Peer review marks at initial stage: 3.5/10

Average Peer review marks at publication stage: 7.0/10

Reviewer(s) detail:

Dr. Liliya Logoyda, Horbachevsky Ternopil State Medical University, Ukraine, logojda@tdmu.edu.ua

Dr. Rer. Nat. Muhaimin, University of Jambi, Indonesia, muhaimin_73@yahoo.de