EVALUATION OF ANTIOXIDANT ACTIVITY OF EXTRACT COMBINATION OF GINGER AND LEMONGRASS

  • Faradiba Faculty of Pharmacy, Universitas Muslim Indonesia.
  • Rezki Amriati Syarif Faculty of Pharmacy, Universitas Muslim Indonesia.
  • Anggi Anggrayni Faculty of Pharmacy, Universitas Muslim Indonesia.
  • Elyana Praditha Faculty of Pharmacy, Universitas Muslim Indonesia.
  • Alifiya Reski Amalia Faculty of Pharmacy, Universitas Muslim Indonesia.
10.22270/ujpr.v9i6.1232

Keywords:

Combination, Cymbopogon citratus, DPPH assay, free radical, Zingiber officinale

Abstract

Aim and objective: This study to determine the antioxidant activity of the combination of ginger (Zingiber officinale) and lemongrass (Cymbopogon citratus) on reducing DPPH (2,2-diphenyl-1-picrylhydrazyl).

Methods: Quantitative measurement of the antioxidant activity of ginger and lemongrass extracts, as well as a combination of both with a concentration ratio of 1:1, 2:1, 1:2 using a UV-Vis spectrophotometer at a wavelength of 516 nm to determine the IC50 value.

Results: IC50 value of ginger extract 10.76 µg/mL, lemongrass extract 26.69 µg/mL, IC50 value 6.69 µg/mL for combination with concentration ratio 1:1, IC50 value 3.32 µg/mL for combination with concentration ratio 2:1. IC50 value 9.34 µg/mL for combination with concentration ratio 1:2

Conclusions: The combination of ginger and lemongrass extracts has synergistic antioxidant activity that can increase the antioxidant effect from the strong category to very strong category.

                   

Peer Review History:

Received 17 October 2024;   Reviewed 9 November; Accepted 18 December; Available online 15 January 2025

Academic Editor: Dr. Ahmad Najiborcid22.jpg, Universitas Muslim Indonesia,  Indonesia, ahmad.najib@umi.ac.id

Average Peer review marks at initial stage: 5.5/10

Average Peer review marks at publication stage: 7.0/10

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Published

2025-01-15

How to Cite

Faradiba, R. A. Syarif, A. Anggrayni, E. Praditha, and A. R. Amalia. “EVALUATION OF ANTIOXIDANT ACTIVITY OF EXTRACT COMBINATION OF GINGER AND LEMONGRASS”. Universal Journal of Pharmaceutical Research, vol. 9, no. 6, Jan. 2025, doi:10.22270/ujpr.v9i6.1232.

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