THE ROLE OF POLYSACCHARIDE AEROGEL IN TISSUE REGENERATION AND REPAIR

Ezegbe Chekwube Andrew; Ezegbe Amarachi Grace; Anikwe Chidera Celestine; Odo Kenechi Benjamin; Onyia Oluebube Chisom; Agu-kalu Amarachi; Ugorji Anita Chidera; Uchenna Chiamaka Precious

doi:10.22270/ujpr.v10i1.1276

Ezegbe Chekwube Andrew Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria. Nanoscience and Advanced Materials, Graduate Program (PPG-Nano), Federal University of ABC, Avenida dos Estados, 5001, 09210-580, Santo Andre, Sao Paulo, Brazil.
Ezegbe Amarachi Grace Department of Home Science and Management, University of Nigeria, Nsukka, Nigeria.
Anikwe Chidera Celestine Department of Clinical Pharmaceutical and Biological Sciences, University of Hertfordshire, England, United Kingdom.
Odo Kenechi Benjamin Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria.
Onyia Oluebube Chisom Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria.
Agu-kalu Amarachi Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria.
Ugorji Anita Chidera Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria.
Uchenna Chiamaka Precious Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria.

10.22270/ujpr.v10i1.1276

Keywords:

Aerogel, biomaterials, biomedicine, material science, porosity

Abstract

Aerogel-based biomaterial is an important subject in materials sciences due to their vast attention in different sectors. These materials possess unique properties that distinguish them such as low density. In the area of tissue engineering, there application has been documented in areas such as blood vessel, soft tissue, nerves, bone and cartilage.There are several steps involved in aerogel preparation. The first step involves the appropriate selection of a precursor material such as polymers, silica or carbon. Aerogels have a unique property which includes the composition of mesoporous solid colloids that possess a light weight and a porous frame work structure. Aerogels also possess unique extraordinary physicochemical properties.Tissue engineering is a broad term that encompasses on using biocompatible materials to repair and replace damaged tissues. Notwithstanding, its diverse applications over the years, tissue engineering have had persistent hurdles which include the need to develop new novel biomaterials This article seeks to review the properties of aerogel and their preparation processes. The review also documented the challenges from current studies and future prospects were also discussed.

Peer Review History:

Received 2 December 2024; Reviewed 11 January 2025; Accepted 14 February; Available online 15 March 2025

Academic Editor: Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622, Giza, Egypt, gehankandeel9@yahoo.com